The Y-Chromosome STRs Profile of Louis XVII (1785-1795?)

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Y Chromosome-Specific STRs

The Y chromosome is one of the smallest human chromosomes with an average size of 60 million base pairs (Mb). Between X and Y chromosomes, exchange is limited to small pseudoautosomal regions (PAR) of the X-Y pair (see Figure 1). During male meiosis, recombination only takes place at the most distal short arm (PAR 1) and at the tip of the Y chromosome long arm (PAR 2). For most of its length (t...

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Detection of Y Chromosome Microdeletions and Hormonal Profile Analysis of Infertile Men undergoing Assisted Reproductive Technologies

Objective Y chromosome deletions (YCDs) in azoospermia factor (AZF) region are associated with abnormal spermatogenesis and may lead to azoospermia or severe oligozoospermia. Assisted reproductive technologies (ART) by intracytoplasmic sperm injection (ICSI) and testicular sperm extraction (TESE) are commonly required for infertility management of patients carrying YCDs. The aim of this study w...

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Mutation Rate Estimates for 110 Y-chromosome Strs Combining Population and 1 Father-son Pair Data 2 3 Running Title: Mutation Rate Estimates for Y-strs 21

22 23 Y-chromosome microsatellites (Y-STRs) are typically used for kinship analysis and 24 forensic identification as well as for inferences on population history and evolution. All 25 applications would greatly benefit from reliable locus-specific mutation rates, to improve 26 forensic probability calculations and interpretations of diversity data. However, estimates of 27 mutation rate from f...

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ژورنال

عنوان ژورنال: International Journal of Sciences

سال: 2019

ISSN: 2305-3925,2410-4477

DOI: 10.18483/ijsci.1899